Italian
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
tenuifolin/polygala
Il collegamento viene salvato negli appunti
12 risultati
Tenuifolin, a saponin derived from Radix Polygalae, exhibits sleep-enhancing effects in mice.
Solo gli utenti registrati possono tradurre articoli
Entra registrati
BACKGROUND
Radix Polygalae, the dried root of Polygala tenuifolia, has been extensively used as a traditional Chinese medicine for promoting intelligence and tranquilization. Polygalasaponins extracted from the root of P. tenuifolia possess evident anxiolytic and sedative-hypnotic activities.
Protective effects of tenuifolin isolated from Polygala tenuifolia Willd roots on neuronal apoptosis and learning and memory deficits in mice with Alzheimer's disease.
Solo gli utenti registrati possono tradurre articoli
Entra registrati
The roots of Polygala tenuifolia Willd have a long history of being used as a traditional Chinese medicine for the treatment of insomnia, forgetfulness, sorrow and depression. Tenuifolin (TEN) has been isolated from Polygala tenuifolia Willd roots, and this study was carried out to investigate the
Tenuifolin, an extract derived from tenuigenin, inhibits amyloid-beta secretion in vitro.
Solo gli utenti registrati possono tradurre articoli
Entra registrati
OBJECTIVE
Previous studies have shown that tenuigenin, a crude extract of Polygala tenuifolia Willd. that is commonly used in traditional Chinese herbal medicine for memory loss, can reduce the secretion of Abeta from cultured cells. However, the mechanism underlying this effect and the active
Tenuifolin Attenuates Amyloid-β42-Induced Neuroinflammation in Microglia Through the NF-κB Signaling Pathway
Solo gli utenti registrati possono tradurre articoli
Entra registrati
Background: Inflammation and oxidative stress are believed to play an important role in the pathogenesis of Alzheimer's disease (AD). Tenuifolin (TEN) is a natural neuroprotective compound extracted from Polygala tenuifolia Willd, which
Polygala tenuifolia: a source for anti-Alzheimer's disease drugs
Solo gli utenti registrati possono tradurre articoli
Entra registrati
Context: Alzheimer's disease (AD) is a chronic neurodegenerative disease that originates from central nervous system lesions or recessions. Current estimates suggest that this disease affects over 35 million people worldwide. However, lacking effective drugs is the biggest handicap in
[HPLC Fingerprint and Active Components Determination of Polygala tenuifolia Root Bark and Root].
Solo gli utenti registrati possono tradurre articoli
Entra registrati
OBJECTIVE
To compare the difference between Polygala tenuifolia root bark and root using HPLC fingerprint analysis and active components determination.
METHODS
Three main characteristic components including tenuifolin, polygalaxanthone III, and 3, 6'-disinapoly sucrose in different Polygala
[Rationality of commodity criteria and traditional breeding of Polygala tenuifolia based on agronomic traits and determination of chemical components].
Solo gli utenti registrati possono tradurre articoli
Entra registrati
The agronomic traits (plant height, root diameter, root length, first lateral root height, lateral root amount, root weight) of 18 Polygala tenuifolia samples with different agronomic traits were analyzed, respectively. HPLC was used to analyze three main characteristic components including
Chemical investigation of the roots of Polygala sibirica L.
Solo gli utenti registrati possono tradurre articoli
Entra registrati
OBJECTIVE
To investigate the chemical constituents of the roots of Polygala sibirica L. (Polygalaceae)
METHODS
The isolation was performed by solvent extraction and various chromatographic techniques, including silica gel, Sephadex LH-20, ODS, semi-preparative HPLC, and preparative TLC. The chemical
Anti-angiogenic effect of triterpenoidal saponins from Polygala senega.
Solo gli utenti registrati possono tradurre articoli
Entra registrati
Senegasaponins [senegin II (1), senegin III (2), senegin IV (3), senegasaponin a (4), and senegasaponin b (5)] from Polygala senega were re-discovered as selective anti-proliferative substances against human umbilical vein endothelial cells (HUVECs). Senegasaponins (1-5) showed anti-proliferative
[Intestinal Absorption Characteristics and Mechanism of Polygala tenuifolia Hydrolysate in Rats].
Solo gli utenti registrati possono tradurre articoli
Entra registrati
OBJECTIVE
To evaluate the absorption feature and mechanism of tenuifolin(TF) and polygalaxanthone III (PT) in different intestinal parts of rats and the impact of MRP2 and P-glycoprotein (P-gp) on it.
METHODS
In situ unidirectional perfusion was used to detect the concentration of TF and PT through
An LC-MS/MS method for simultaneous determination of three Polygala saponin hydrolysates in rat plasma and its application to a pharmacokinetic study.
Solo gli utenti registrati possono tradurre articoli
Entra registrati
BACKGROUND
Radix Polygala has a long history of use as a sedative in traditional Chinese medicine and its major ingredients are saponins, which are recognized effective in memory improvement but highly toxic to gastricintestinal mucosa. Polygala saponin hydrolysates (PSH), an alkaline hydrolysis
The gastrointestinal irritation of polygala saponins and its potential mechanism in vitro and in vivo.
Solo gli utenti registrati possono tradurre articoli
Entra registrati
Processing alters the pharmacological activity and reduces the gastrointestinal toxicity of the polygalae. To investigate the effect of processing, different glycosyl substituent products were tested. Hypnotic and subhypnotic doses of pentobarbital-induced sleep tests on mice were used to evaluate
Il database di erbe medicinali più completo supportato dalla scienza
- Funziona in 55 lingue
- Cure a base di erbe sostenute dalla scienza
- Riconoscimento delle erbe per immagine
- Mappa GPS interattiva - tagga le erbe sul luogo (disponibile a breve)
- Leggi le pubblicazioni scientifiche relative alla tua ricerca
- Cerca le erbe medicinali in base ai loro effetti
- Organizza i tuoi interessi e tieniti aggiornato sulle notizie di ricerca, sperimentazioni cliniche e brevetti
Digita un sintomo o una malattia e leggi le erbe che potrebbero aiutare, digita un'erba e osserva le malattie ei sintomi contro cui è usata.
* Tutte le informazioni si basano su ricerche scientifiche pubblicate
