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viroallosecurinine/flueggea
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3 risultati
Cytotoxic principles of Securinega virosa: virosecurinine and viroallosecurinine and related derivatives.
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Virosecurinine (1) and viroallosecurinine (2) were isolated as two cytotoxic alkaloids from the leaves of Securinega virosa. A comparison of the cytotoxicity of 1 and several of its derivatives indicates that an alpha,beta- and a gamma,delta-unsaturated lactone located in a strained ring system,
[Studies on chemical constituents from leaves of Securinega suffruticosa].
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OBJECTIVE
To investigate the chemical constituents of Securinega suffruticosa.
METHODS
It was isolated and purified by silica gel chromatography. Their structures were elucidated by means of spectral analysis.
RESULTS
Four compounds were isolated and identified as ent-phyllanthidine (1),
Callus of Securinega suffruticosa, a cell line accumulates dextro Securinega alkaloids.
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Investigations on callus cultures of Securinega suffruticosa indicated that the cell line of S. suffruticosa callus was able to accumulate four known Securinega alkaloids with dextro rotation but not levo rotation as reported before: virosecurinine (1), viroallosecurinine (2),
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