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Erythema infectiosum or fifth disease is one of several possible manifestations of infection by parvovirus B19.The name 'fifth disease' comes from its place on the standard list of rash-causing childhood diseases, which also includes measles (first), scarlet fever (second), rubella (third), Dukes' disease (fourth, but is no longer widely accepted as distinct from scarlet fever), and roseola (sixth).

Fifth disease starts with a low-grade fever, headache, rash, and cold-like symptoms, such as a runny ...