[Chemical constituents in the roots of Salvia przewalskii Maxim].

OBJECTIVE

To investigate the chemical composition of the root of Salvia przewalskii Maxim.

METHODS

Compounds were isolated by silica gel column chromatography. Structures of these compounds were elucidated by spectral analysis (EI-MS, FAB-MS, 1HNMR, 13CNMR, 1H-1H COSY, 1H-13C COSY, HMBC, NOESY) and phytochemical properties.

RESULTS

Eight compounds were isolated and identified as: tanshinone II-A (I), crypotanshinone (II), przewaquinone A (III), sugiol (IV), ursolic acid (V), 2 alpha, 3 alpha-dihydroxy urs-12-ene-28-acid (VI), oleanolic acid (VII), and neo-przewaquinone A (VIII).

CONCLUSIONS

Compound VIII is a new compound, and compound II, IV, V, VI and VII are isolated from this plant for the first time.