[Ethyl Acetate-Soluble Chemical Constituents from Callicarpa kwangtungensis (II)].

OBJECTIVE

To study the ethyl acetate-soluble chemical constituents of Callicarpa kwangtungensis.

METHODS

The chemical constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and MPLC. Their chemical structures were elucidated on the basis of special analysis.

RESULTS

Eleven compounds were isolated from the ethyl acetate-soluble part of Callicarpa kwangtungensis, whose structures were elucidated as 4-methoxybenzoic acid (1), 3,4-dihydroxybenzoic acid (2), 4-hydroxy cinnamic acid(3), phenyl-β-D-glucopyranoside (4), 3,4,5-trimethoxyphenyl-β-D-glucopyranoside (5), 2α,3β,22β,23-tetrahydroxyursolic-12-en-28-oic acid (6), 2α,3β,6β,19α-tetrahydroxy-urs-12-en-28-O-β-D-glucopyranoside (7), 2β,3β,6β,16α-tetrahydroxy-olean-12-en-28-O-β-D-glucopyranoside (8), (3S, 6E, 10R)-10-β-D-glucopyranosyloxy-3,11-dihydroxy-3,7,11-trimethyldodeca-1,6-diene (9), icariside C5(10), and (2E, 6E)-10-β-D-glucopyranosyl-1, 11-dihydroxy-3, 7, 11-trimethyldodeca-2,6-diene (11).

CONCLUSIONS

Compounds 4 - 11are isolated from Callicarpa genus for the first time, compounds 1 - 3 are isolated from this plant for the first time.