3 תוצאות
Products of lipoxygenase metabolism play a role in the pathogenesis of psoriasis. Four protoberberine alkaloids, berberine, oxyberberine, jatrorrhizine, columbamine, and two aporphine alkaloids, magnoflorine, and corytuberine, isolated from Mahonia aquifolium, were tested for lipoxygenase
In the present study we tested the effect of four aporphine alkaloids, corytuberine, magnoflorine, isothebaine and isocorydine, on the isolated rat aorta. Corytuberine and magnoflorine showed little effect as relaxants in KCl- and noradrenaline-induced contractions. They did not inhibit the
Cytochrome P450s (P450) play a key role in oxidative reactions in plant secondary metabolism. Some of them, which catalyze unique reactions other than the standard hydroxylation, increase the structural diversity of plant secondary metabolites. In isoquinoline alkaloid biosyntheses, several unique