Diabetes

Subcutaneous injection of 0.24 mg/kg Mozobil once at 8:30am

Mozobil

Policlinico Universitario, Azienda Ospedaliera di Padova

Stem Cell Mobilization With Plerixafor in Diabetic vs Control Subjects

Mobilization Test of BM Progenitor Cells With Plerixafor / AMD3100: Controlled Parallel Group Comparison Between Diabetic and Non Diabetic Subjects

To evaluate the differences of CD34+ cells mobilization from the bone marrow to the peripheral blood induced by a single sc injection of Mozobil in diabetic patients versus non diabetic controls.
Clinical response variable: comparison of the fold change in CD34+ peripheral cell count in diabetic versus non diabetic controls after Mozobil administration (with collection of safety and tolerability data).

to evaluate whether Mozobil monotherapy is able to induce a significant CD34+ stem cells mobilization in diabetic patients (intra-group comparison).
Clinical response variable: detection of a significant fold-change in CD34+ peripheral cell count versus baseline in diabetic patients.

To evaluate the differences in mobilization of EPC (CD34+KDR+) from the bone marrow to the peripheral blood induced by a single sc injection of Mozobil in diabetic patients versus non diabetic controls (inter-group comparison).
Clinical response variable: comparison of the fold change in CD34+ KDR+ peripheral cell count in diabetic versus non diabetic controls after Mozobil administration (with collection of safety and tolerability data).

To evaluate whether Mozobil monotherapy is able to induce a significant EPC mobilization in diabetic patients (intra-group comparison).
Clinical response variable: detection of a significant fold-change in CD34+KDR+ peripheral cell count versus baseline in diabetic patients

diabetic angiopathies/כאב ראש

Stem Cell Mobilization With Plerixafor in Diabetic vs Control Subjects

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע