All eligible migrants will be offered opt-out IGRA blood test to screen for for latent Tuberculosis infection

Latent Tuberculosis

All eligible pregnant migrants will be offered an opt-out screening IGRA blood test for latent Tuberculosis infection

IGRA blood test used as a tool for opt-out screening for latent Tuberculsis infection

Royal London Hospital

Whipps Cross Hospital

Newham University Hospital

Screening for Tuberculosis in Pregnancy

Uptake, Effectiveness and Acceptability of Routine Screening of Pregnant Migrants for Latent Tuberculosis Infection in Antenatal Care: a Feasibility Study

Proportion of eligible women who are screened, all pregnant women booked for antenatal care will be screened if fulfilling the eligibility criteria, and we will monitor the reasons for ineligibility.

Rates of LTBI prevalence in the pregnant migrant population as assessed by the proportion of IGRA positive migrants.

Rates of active TB identified in pregnant migrants during the study period and time to diagnosis.

Acceptability of interventions such as educational material to increase uptake of LTBI screening assessed by interviews and focus groups.

Acceptability of LTBI screening (Perceptions, barriers and facilitators) among pregnant women assessed by qualitative methods (interviews, focus groups) and a standardised non-validated questionnaire.

Acceptability of treatment for LTBI postpartum and timing of treatment as assessed by interviews and focus groups.

Identification of barriers influencing uptake of LTBI treatment of migrant women postpartum assessed by interviews and focus groups

Acceptability of interventions to increase LTBI treatment postpartum such as SMS messaging assessed by interviews and focus groups.

Acceptability of LTBI screening from a health care providers' perspective assessed by interviews and focus groups.

Standardised non-validated LTBI knowledge questionnaires at the beginning of pregnancy and after delivery to assess change in knowledge and awareness about active TB/ LTBI amongst migrant women.

Change in knowledge and awareness about active TB/LTBI amongst healthcare providers assessed by a quiz at the beginning and end of the study evaluating the knowledge gained through the E-learning module and educational programme.

Calculated as total cost of offering IGRA in antenatal care and comparing it to total cost of offering IGRA in primary care.

Queen Mary University of London

University College, London

City, University of London

Imperial College London

Observational study assessing the feasibility and acceptability of opt-out screening for latent Tuberculosis infection amongst pregnant migrants in antenatal clinics. All pregnant migrants who meet the inclusion criteria will be offered an opt-out IGRA blood test as screening for latent TB infection

latent tuberculosis/עייפות

Screening for Tuberculosis in Pregnancy

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע