Discovery of new drug binding sites on well-established targets is of great interest as it facilitates the design of new mechanistic inhibitors to overcome the acquired drug resistance. Small chemical fragments can easily enter and bind to the cavities on the protein surface. Thus, they can be used
Abstract Pleural inflammation underlies the formation of most exudative pleural effusions and the plasma kallikrein-kinin system (KKS) is known to contribute. Mesothelial cells are the predominant cell type in the pleural cavity, but their potential role in plasma KKS activation and BK production
The objective of the present work was to examine the bacterial flora associated with the oral cavity of Indian cobra and to study their antibiogram.Oral swabs, collected from six healthy (4 males and 2 females) adult cobra, were subjected to microbiological