pristimerin/maytenus

הקישור נשמר בלוח

מאמריםניסויים קלינייםפטנטים

בחר סוג מיון

עמוד 1 מ 16 תוצאות

Antiproliferative activity of pristimerin isolated from Maytenus ilicifolia (Celastraceae) in human HL-60 cells.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Pristimerin has been shown to be cytotoxic to several cancer cell lines. In the present work, the cytotoxicity of pristimerin was evaluated in human tumor cell lines and in human peripheral blood mononuclear cells (PBMC). This work also examined the effects of pristimerin (0.4; 0.8 and 1.7 microM)

Antifungal activity of maytenin and pristimerin.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Fungal infections in humans have increased alarmingly in recent years, particularly in immunocompromised individuals. Among the infections systemic candidiasis, aspergillosis, cryptococcosis, paracoccidioidomycosis, and histoplasmosis mortality are more prevalent and more severe in humans. The

Anticytomegalovirus activity of pristimerin, a triterpenoid quinone methide isolated from Maytenus heterophylla (Eckl. & Zeyh.).

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

We examined the anticytomegalovirus properties of four compounds: pristimerin, the pristimerin analogue, lupeol and 2-acetylphenol-1-beta-D-glucopyranosyl (1 --> 6)-beta-D-xylpyranoside (acetophenol glycoside), isolated from Maytenus heterophylla, a Kenyan medicinal plant. The effects were studied

Evaluation of antioxidant capacity and synergistic associations of quinonemethide triterpenes and phenolic substances from Maytenus ilicifolia (Celastraceae).

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

This work describes the isolation of the secondary metabolites identified as the quinonemethides maytenin (1) and pristimerin (2) from Maytenus ilicifolia extracts obtained from root barks of adult plants and roots of seedlings and their quantification by high performance liquid chromatography

CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The native Brazilian plant Maytenus ilicifolia accumulates a set of quinone methide triterpenoids with important pharmacological properties, among which maytenin, pristimerin and celastrol that accumulate exclusively in the root bark of this medicinal plant. The first committed step in the quinone

Triterpene trimers from Maytenus scutioides: cycloaddition compounds?

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התחבר הרשם

Two novel trimers, triscutins A and B (1 and 2), based on pristimerin triterpene units, were isolated and characterized from Maytenus scutioides. Their structures were determined on the basis of spectroscopic evidence, including 1H-13C heteronuclear correlation (HMQC), long-range correlation with

A new bioactive norquinone-methide triterpene from Maytenus scutioides.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

By antimicrobial and cytotoxic-guided fractionation, a bioactive norquinone-methide triterpene, 15 alpha-hydroxypristimerin, was isolated from a South American medicinal plant, Maytenus scutioides. Its structure was determined on the basis of spectroscopic evidence. Successful chemical

Quantitative determination for cytotoxic Friedo-nor-oleanane derivatives from five morphological types of Maytenus ilicifolia (Celastraceae) by reverse-phase high-performance liquid chromatography.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Five different morphological types of Maytenus ilicifolia of the same age and harvested under the same conditions showed distinct accumulations of some friedo-nor-oleananes. A rapid, sensitive and reliable reverse-phase HPLC method (employing an external standard) was used for the determination of

Antiprotozoal activity of quinonemethide triterpenes from Maytenus ilicifolia (Celastraceae).

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The present study describes the leishmanicidal and trypanocidal activities of two quinonemethide triterpenes, maytenin (1) and pristimerin (2), isolated from Maytenus ilicifolia root barks (Celastraceae). The compounds were effective against the Trypanosomatidae Leishmania amazonensis and Leishmania

Biosynthesis of friedelane and quinonemethide triterpenoids is compartmentalized in Maytenus aquifolium and Salacia campestris.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Maytenus aquifolium (Celastraceae) and Salacia campestris (Hippocrateaceae) species accumulate friedelane and quinonemethide triterpenoids in their leaves and root bark, respectively. Enzymatic extracts obtained from leaves displayed cyclase activity with conversion of the substrate oxidosqualene to

Development and Validation of an HPLC-PDA Method for Biologically Active Quinonemethide Triterpenoids Isolated from Maytenus chiapensis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Background: Quinonemethide triterpenoids, known as celastroloids, constitute a relatively small group of biologically active compounds restricted to the Celastraceae family and, therefore, they are chemotaxonomic markers for this family. Among this particular type of metabolite, pristimerin

Ecological Insights to Track Cytotoxic Compounds among Maytenus ilicifolia Living Individuals and Clones of an Ex Situ Collection.

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התחבר הרשם

Biodiversity is key for maintenance of life and source of richness. Nevertheless, concepts such as phenotype expression are also pivotal to understand how chemical diversity varies in a living organism. Sesquiterpene pyridine alkaloids (SPAs) and quinonemethide triterpenes (QMTs) accumulate in root

Insecticidal activity of Maytenus species (Celastraceae) nortriterpene quinone methides against codling moth, Cydia pomonella (L.) (Lepidoptera: tortricidae).

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The insecticidal effects of nortriterpene quinone methides (pristimerin, tingenonee, and 20-alpha-hydroxytingenone) are reported for the first time. The natural products were isolated from Maytenus sp. (Celastraceae) and their effects tested on larvae of codling moth (Cydia pomonella, Lepidoptera:

Dihydro-β-agarofurans from the roots of the Australian endemic rainforest tree Maytenus bilocularis act as leucine transport inhibitors.

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התחבר הרשם

Phytochemical studies of the roots of the Australian plant, Maytenus bilocularis, resulted in the identification of six previously undescribed dihydro-β-agarofuran sesquiterpenoids, bilocularins D-I, along with three known natural products, namely

Antimitotic quinoid triterpenes from Maytenus chuchuhuasca.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Four cytotoxic quinoid triterpenes, tingenone (1), 22 beta-hydroxytingenone (2), pristimerin (3), and celastrol (4), isolated from Maytenus chuchuhuasca, potently inhibit the polymerization of tubulin.

קודם
1
2
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Herbal & Natural Medicine

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