virilism/ניוון ביולוגיה

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מאמריםניסויים קלינייםפטנטים

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עמוד 1 מ 32 תוצאות

[Syndrome of bilateral degeneration of ovaries, combined with secondary amenorrhea and virilization].

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Testicular degeneration in three patients with the persistent müllerian duct syndrome.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The persistent müllerian duct syndrome, characterized by the presence of uterus and tubes in males, is a familial disorder due to defects of synthesis or action of anti-müllerian hormone, a Sertoli cell glycoprotein responsible for the regression of müllerian derivatives in normal male fetuses.

Spinal and bulbar muscular atrophy: androgen receptor dysfunction caused by a trinucleotide repeat expansion.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Kennedy's disease (spinal and bulbar muscular atrophy) is an X-linked form of motor neuron disease that affects adult men. The syndrome is characterized by progressive atrophy of the limb muscles, pelvic and shoulder girdles and dysphagia and dysarthria, and is caused by the degeneration of spinal

[Leydig cell tumor with pronounced virilization].

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A report is given on the rare case of a hormonactive Leydig cell-tumor in a 52-year-old patient. In spite of virilization symptoms of many years' standing, it was only because of multiple troubles with a great uterus myomatosus that she was admitted to the hospital. An ovarian tumor existing at the

[Virilization in women. Clinical and therapeutic aspects].

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Androgenization in women can be divided, from a clinical standpoint, in two groups: a major form (with hirsutism, seborrhea, acne, hair loss, menstrual irregularities, masculinization of muscles and voice, mammary atrophy) and a minor one, with skin changes only (in particular hirsutism) with or

Postnatal androgenization induces premature aging of rat ovaries.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

In the present paper, we report that ovaries of adult rats treated with testosterone propionate (TP) on a critical postnatal Day 5 exhibit histologic and immunohistochemical findings which resemble those of the anovulatory ovaries in middle-aged female rats. The sterile rat model has been long known

Misdiagnosed ovarian Krukenberg tumor during pregnancy with virilization.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Krukenberg tumor with pregnancy is rare but it is a challenge for treatment and diagnosis. The authors report a case of a 29-week pregnant patient with a massive bilateral Krukenberg tumor which was misdiagnosed as myoma preoperatively and as ovarian stromal tumor intraoperatively. Prenatally the

Recovery of reproductive function following androgen abuse.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

OBJECTIVE To summarize recent data on the adverse reproductive consequences of androgen abuse, focusing on the recovery of reproductive function following androgen discontinuation. RESULTS Evidence is mostly based on case reports and observational studies. Androgen abuse leads to a state of

Long polyglutamine tracts in the androgen receptor are associated with reduced trans-activation, impaired sperm production, and male infertility.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The X-linked androgen receptor (AR) gene contains two polymorphic trinucleotide repeat segments that code for polyglutamine and polyglycine tracts in the N-terminal trans-activation domain of the AR protein. Changes in the lengths of these polymorphic repeat segments have been associated with

Testicular function after torsion.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A group of 20 patients with torsion was investigated. The study indicated that immediate surgical intervention with a period of torsion of the testis of less than 6 h will prevent impairment of testicle function. The histology of testicular biopsies taken from such patients revealed only

Testicular failure and male infertility in the monogenic Mulibrey nanism disorder.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

BACKGROUND Few monogenic mutations causing human male infertility have been identified to date. OBJECTIVE We studied pubertal development and fecundity in males with Mulibrey nanism (MUL) caused by mutations in the TRIM37 gene. METHODS Twenty-eight male MUL patients of the Finnish national cohort

Anabolic steroids in athletics: how well do they work and how dangerous are they?

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The use of anabolic drugs by athletes who wish to increase lean body mass and improve muscular strength is widespread, especially among elite weight-trained athletes. The current regimens used for steroid doping include combinations of injectable and oral preparations of steroids at doses 10 to 40

Assessment of androgen receptor function in genital skin fibroblasts using a recombinant adenovirus to deliver an androgen-responsive reporter gene.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Mutations of the androgen receptor (AR) cause defects in virilization and can result in a spectrum of phenotypic abnormalities of male sexual development that includes patients with a completely female phenotype (complete testicular feminization) and individuals with less severe defects of

Evolution of the primate androgen receptor: a structural basis for disease.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Androgen effects mediated by the androgen receptor (AR) are essential for male reproductive development and virilization. Comparison of AR DNA coding sequence from five primate species, Homo sapiens (human), Pan troglodytes (chimpanzee), Papio hamadryas (baboon), Macaca fascicularis (macaque), and

Cushing's syndrome in infancy: difficulties in diagnosis and adrenal autotransplantation after therapeutic adrenalectomy.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A two-month-old female with clinical manifestations of Cushing's syndrome including mild virilization exhibited an unusual steroid pattern illustrating difficulties in diagnosis of this disorder in infancy. Unequivocal abnormalities were limited to serial elevations of serum cortisol concentration,

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