Grass Sensitisation and Allergic Rhinitis in Thai Patients
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スポンサー
Mahidol University
共同編集者
National Research Council of Thailand
臨床試験: NCT01686022
BioSeek: NCT01686022
キーワード
概要
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.
説明
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
日付
| 最終確認済み: | 08/31/2016 |
| 最初に提出された: | 09/11/2012 |
| 提出された推定登録数: | 09/13/2012 |
| 最初の投稿: | 09/16/2012 |
| 最終更新が送信されました: | 09/12/2016 |
| 最終更新日: | 09/13/2016 |
| 実際の研究開始日: | 09/30/2012 |
| 一次完了予定日: | 09/30/2015 |
| 研究完了予定日: | 09/30/2015 |
状態または病気
Allergy to Grass Pollen
Allergic Rhinitis Due to Weed Pollens
介入/治療
Other: Pollen Allergy
段階
-
アームグループ
| 腕 | 介入/治療 |
|---|---|
| Pollen Allergy Pollen allergy and control will have the same intervention, ie. Skin prick test and collect serum samples.Then measure the specificIgE, immunoblot, and ELISA inhibition | Other: Pollen Allergy serum specific IgE binds to grass extract by immunoblot |
適格基準
| 研究の対象となる年齢 | 10 Years に 10 Years |
| 研究に適格な性別 | All |
| サンプリング方法 | Non-Probability Sample |
| 健康なボランティアを受け入れる | はい |
| 基準 | Inclusion Criteria: - Allergic rhinitis patients age 10-50 years old - Control: healthy volunteer age 18-50 years old Exclusion Criteria: - Chronic illness such as cardiovascular diseases, liver diseases - History of anaphylaxis - Pregnancy |
