Study of Some Risk Factors for Developing RA
キーワード
概要
説明
Patients will answer the following the questationnaire:
Name age gender
1 Socio echonomic status (average salary \year) (Education) (Job) (residence)
1. Body mass index (height\wt2)
2. Disease duration in months.
3. Smoking (yes) (No) Passive smoker Ex smoker
4. Reproductive history:
- age of menarche….
- menstrual cycle….. regular or not……. P / C
- How many pregnancies…….. living.
- Abortion.
- patient age at first birth (….).
- breast feeding…..(yes)…….(no)
- use of contraceptives (yes)…pills injections IUD (N0)……
- Does patient get pregnant during disease?...(Yes)……(no)….. Does the arthritis improved (…)or got worse (…..) -flared during the purpurium.(yes) … (No)
- age of menupause…. 10 Exposure to sun….(yes)…..(No) 11 -Theraputic history… (Newly diagnosed)
- (Previously diagnosed),
- Does the patient receiving ttt? (yes) (Steroid)……. (NSAIDS)……. (2nd line drugs) (.Methotrexat(.…), Leflonamide (….) Hydroquine(….) (NO)……..
- The study will include 100 patients fullfilling ACR 2010
- Patients well subjected to
- Through clinical examination with emphysis on joints examination
- venous blood sampling will withdrawn and the following investigations will be done.
- Serum VIT D level
- Serum calcium and phosphorus
- Anti cyclic citrullinated peptide.
- ESR
日付
| 最終確認済み: | 07/31/2018 |
| 最初に提出された: | 07/10/2018 |
| 提出された推定登録数: | 08/07/2018 |
| 最初の投稿: | 08/09/2018 |
| 最終更新が送信されました: | 08/07/2018 |
| 最終更新日: | 08/09/2018 |
| 実際の研究開始日: | 08/14/2018 |
| 一次完了予定日: | 09/14/2018 |
| 研究完了予定日: | 09/19/2018 |
状態または病気
段階
アームグループ
| 腕 | 介入/治療 |
|---|---|
| Rheumatoid arthritis patients complete blood count, Erythrocyte sedimentation rate, C reactive protien ,rheumatoid factor,Anti cyclic citrullinated peptide antibody | |
| healthy control complete blood count, Erythrocyte sedimentation rate, C reactive protien ,rheumatoid factor,Anti cyclic citrullinated peptide antibody |
適格基準
| 研究に適格な性別 | All |
| サンプリング方法 | Non-Probability Sample |
| 健康なボランティアを受け入れる | はい |
| 基準 | Inclusion Criteria: - patients with rheumatoid arthritis diagnosed based on american collegue of rheumatology 2010 criteria with no history of vit D therapy Exclusion Criteria: - patients with rheumatoid arthritis on vit D supplements - patient refusal - patient not fullfill american collegue of rheumatology 2010 citeria for diagnosis pf rheumatoid arthritis |
結果
主な結果の測定
1. vitamin D level [one month]
2. Body mass index [one month]
二次的な結果の測定
1. Anti cyclic citrullnated peptide antibodies [one month]
2. Rheumatoid factor antibody [one month]
