The Effect of Berry Extract on Helicobacter Pylori Eradication
キーワード
概要
説明
One-week of triple therapy composed of a proton pump inhibitor plus two antibiotics is currently regarded as the gold standard for HP eradication. However, the eradication rate continues to be disappointing. Poor patient compliance and bacterial resistance are the main factors contributing to treatment failure. Therefore, it is urgently necessary to develop a non-antibiotic alternative therapy to increase the eradication rates of Helicobacter pylori. Some literatures reported that cranberry may inhibit Helicobacter pylori adhesion to the human gastric mucus and may reduce Helicobacter pylori infection in adults. The aims of his experiment were to explore the impact of berry extract on triple therapy for Helicobacter pylori eradication.
日付
| 最終確認済み: | 12/31/2009 |
| 最初に提出された: | 12/28/2009 |
| 提出された推定登録数: | 01/07/2010 |
| 最初の投稿: | 01/10/2010 |
| 最終更新が送信されました: | 01/12/2010 |
| 最終更新日: | 01/13/2010 |
| 実際の研究開始日: | 12/31/2008 |
| 一次完了予定日: | 11/30/2009 |
| 研究完了予定日: | 05/31/2010 |
状態または病気
介入/治療
Dietary Supplement: Berry extract
段階
アームグループ
| 腕 | 介入/治療 |
|---|---|
| Placebo Comparator: Berry | |
| Placebo Comparator: Placebo |
適格基準
| 研究の対象となる年齢 | 18 Years に 18 Years |
| 研究に適格な性別 | All |
| 健康なボランティアを受け入れる | はい |
| 基準 | Inclusion Criteria: - Patients older than 18 Exclusion Criteria: - Pregnancy or breastfeeding - Use of antibiotics 2 weeks prior to inclusion - Previous eradication treatment |
結果
主な結果の測定
1. Eradication rate [4 weeks after Eradication of Helicobacter pylori]
