Dental Malocclusion and Craniofacial Development in OI
キーワード
概要
説明
Investigators will look at dental health in people with OI and will describe teeth misalignment and head and neck defects in individuals with moderate to severe Osteogenesis Imperfecta (OI).
Investigators will look at results from the Longitudinal study of OI to complete the study evaluations. Several x-rays will be performed for this study. Participants will have a 3D scan of the mouth and a Cone Beam CT scan of the jaw at a baseline visit and at 3 years after the baseline visit. These study visits can be at the same time as the Longitudinal Study of OI study visits.
日付
最終確認済み: | 03/31/2020 |
最初に提出された: | 10/11/2016 |
提出された推定登録数: | 10/12/2016 |
最初の投稿: | 10/16/2016 |
最終更新が送信されました: | 04/06/2020 |
最終更新日: | 04/07/2020 |
実際の研究開始日: | 07/31/2016 |
一次完了予定日: | 12/31/2019 |
研究完了予定日: | 11/30/2020 |
状態または病気
段階
適格基準
研究の対象となる年齢 | 10 Years に 10 Years |
研究に適格な性別 | All |
サンプリング方法 | Probability Sample |
健康なボランティアを受け入れる | はい |
基準 | Inclusion Criteria: - Males and females with Clinical diagnosis of OI other than OI type I - Individuals 10 years or older - Participant of the Brittle Bone Disease (BBD) Longitudinal Study (7701) Exclusion Criteria: - Individuals who cannot be correctly positioned for valid radiographic analysis (e.g., due to severe scoliosis or short neck secondary to basilar invagination) - Women who are pregnant |
結果
主な結果の測定
1. Measure teeth misalignment in individuals with moderate to severe OI using scans of the teeth. [5 years]
二次的な結果の測定
1. Determine neck defects in individuals with moderate to severe OI using scans of the neck and jaw. [5 years]