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Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation?

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Sakarya University

キーワード

概要

In this study, the investigators aimed to compare postanesthetic agitation in patients undergoing laparotomic gynecological surgery under general anesthesia using sevoflurane at a fresh gas flow rate of 2 L / min with fresh gas flow rate of 0.5 L / min.

説明

Emergence agitation is a temporary state of mental anxiety that occurs during general anesthesia recovery. It is characterized by emergence agitation, hallucination, excitation, delusion and confusion. Increased hemorrhage due to hypertension may cause serious complications such as injury to the surgical site, patients' self-removal of surgical drains and catheters, and self-extubation. Due to these, emergence agitation results need for additional treatment, psychological stress and increased medical workload for patients and their families.

Emergence agitation after general anesthesia in adult patients was reported up to 20%. However, the ratios are very wide.

In our operating room, the investigators observed that patients with low flow anesthesia were less agitated in the recovery phase than patients with normal flow anesthesia. In our researches, the investigators have not found any studies on the agitation values of patients who underwent low flow anesthesia in the literature.

日付

最終確認済み: 02/29/2020
最初に提出された: 02/14/2019
提出された推定登録数: 02/28/2019
最初の投稿: 03/04/2019
最終更新が送信されました: 03/16/2020
最終更新日: 03/17/2020
実際の研究開始日: 05/31/2018
一次完了予定日: 10/31/2019
研究完了予定日: 10/31/2019

状態または病気

Agitated; State, Acute Reaction to Stress

介入/治療

Drug: Postsurgical Pain

Drug: Postanesthesia nausea and vomiting

段階

段階 4

アームグループ

介入/治療
Active Comparator: Postsurgical Pain
pain is defined as unpleasant sensation that can range from mild, localized discomfort to agony.
Drug: Postsurgical Pain
while patients are in the PACU after general anesthesia, if patients' VAS scores are higher than 3, we will give them 50 mg of deksketoprofen as analgesic.
Active Comparator: Postanesthesia nausea and vomiting
nausea defined as feeling of sickness or discomfort in the stomach that may come with an urge to vomit.
Drug: Postanesthesia nausea and vomiting
while patients are in the PACU after general anesthesia, if patient' Nausea and vomiting scores are higher than 1, we will give them 4 mg of ondansetron

適格基準

研究の対象となる年齢 18 Years に 18 Years
研究に適格な性別Female
健康なボランティアを受け入れるはい
基準

Inclusion Criteria:

- ASA physical status 1 and 2, underwent gynicological laparotomic surgery under general anesthesia, followed up in PACU(postoperative care unit)

Exclusion Criteria:

- ASA 3 or 4, mental retardation, psychiatric disease, history of malignant hyperthermia in patient or her family, neurological disease, morbid obesity, history of asthma and follow-up in the intensive care unit.

結果

主な結果の測定

1. Postanesthetic emergence agitation [30 minutes after general anesthesia recovery]

Emergence agitation is a temporary state of mental anxiety that occurs during general anesthesia recovery. It is characterized by emergence agitation, hallucination, excitation, delusion and confusion. Emergence agitation is defined as the Riker sedation-agitation scale (SAS) score of 5 or more at any time in the PACU. Riker sedation-agitation scale: 7 point is 'Dangerous agitation' 6 point is 'very agitated' 5 point is 'agitated' 4 point is 'calm and cooperative' 3 point is 'sedated' 2 point is 'very sedated' 1 point is 'unarousable'

二次的な結果の測定

1. postanesthetic nausea and vomiting [30 minutes after general anesthesia recovery]

The Nausea-Vomiting score will also assess and 4 mg of Ondansetron iv will be administered to those who had a score of 2 or more. The Nausea-Vomiting score: 0 point: no nausea or vomiting point: the patient has moderate nausea for less than 15 minutes point: the patient has nausea for more than 15 minutes point: the patient has retching or vomiting

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