Green Tea in Breast Cancer Patients
キーワード
概要
日付
| 最終確認済み: | 02/28/2018 |
| 最初に提出された: | 07/28/2009 |
| 提出された推定登録数: | 07/29/2009 |
| 最初の投稿: | 07/30/2009 |
| 最終更新が送信されました: | 03/27/2018 |
| 最終更新日: | 03/29/2018 |
| 実際の研究開始日: | 05/06/2008 |
| 一次完了予定日: | 12/13/2010 |
| 研究完了予定日: | 06/05/2016 |
状態または病気
介入/治療
Dietary Supplement: tea capsules
段階
アームグループ
| 腕 | 介入/治療 |
|---|---|
| Active Comparator: tea capsules 3 tea capsules daily for 3 weeks | Dietary Supplement: tea capsules 3 tea capsules daily for 3 weeks |
| No Intervention: Control No tea capsules |
適格基準
| 研究の対象となる年齢 | 18 Years に 18 Years |
| 研究に適格な性別 | Female |
| 健康なボランティアを受け入れる | はい |
| 基準 | Inclusion Criteria: - Postmenopausal (at least 2 years since last menstrual period) or age 55 or older if prior hysterectomy - Non-current (not with past 6 months) user of menopausal hormones - Mammographic abnormality consistent with any type of incident breast cancer necessitating a diagnostic biopsy (BIRAD IV(b), (c) or V) will be sufficient to draw baseline LFT and complete screening questionnaire. Unless the biopsy confirms incident breast cancer, such subjects will not be included in further research interventions and they will not serve as EGCG treated or control subjects. - Diagnosed with incident breast cancer on the diagnostic biopsy is required for inclusion in the EGCG or control treatment groups. - Non-green tea drinker (less than monthly) - this criteria does not apply to black tea or herbal tea - Provided written informed consent Exclusion Criteria: - Green tea drinker (once per month or more) - History of breast cancer or other cancer including a prior diagnosis of any type of incident breast cancer. - Known allergy to tea - Abnormal liver enzymes (plus or minus 10% of the normal ranges). |
結果
主な結果の測定
1. level of reduction in proliferation or increase in apoptosis in association with short-term EGCG [At surgery]
