Perioperative Fluid Therapy in Pediatric Patients Undergoing Penile Hypospadias Repair
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スポンサー
Cairo University
臨床試験: NCT04444089
BioSeek: nct04444089
キーワード
概要
Optimization of perioperative fluid management is important for preventing adverse events, such as hypovolemia, cardiogenic shock, volume overload, and pulmonary edema, in both adult and pediatric patients. If the intravascular (IV) fluid volume is not optimized, pediatric patients are at risk of dehydration or volume overload. Perioperative IV fluid therapy is important during and after induction of general anesthesia (GA).The aim of this study is to investigate the difference between conventional and restrictive fluid replacement regimens using lung ultrasound in pediatric patients undergoing penile hypospadias repair, as a surgery with minor fluid loss.
日付
| 最終確認済み: | 06/30/2020 |
| 最初に提出された: | 06/19/2020 |
| 提出された推定登録数: | 06/19/2020 |
| 最初の投稿: | 06/22/2020 |
| 最終更新が送信されました: | 07/12/2020 |
| 最終更新日: | 07/14/2020 |
| 実際の研究開始日: | 06/23/2020 |
| 一次完了予定日: | 07/31/2020 |
| 研究完了予定日: | 07/31/2020 |
状態または病気
Volume Overload
介入/治療
Diagnostic Test: lung ultrasound
段階
-
アームグループ
| 腕 | 介入/治療 |
|---|---|
| Experimental: conventional group, CG receives Ringer's lactate solution at a rate of 4 ml/kg/h for the first-10 kg of body weight, 2 ml/kg/h for the second-10 kg of body weight, and 1 ml/kg/h for each further kg of body weight. The deficit volume is calculated as the maintenance volume multiplied by fasting hours and given as follows: 50% of the volume in the first hour, 25% of the volume in the second hour, and 25% of the volume in the third hour, in addition to the aforementioned maintenance volume | |
| Experimental: restricted group, RG Patients in the RG receives Ringer's lactate solution at a rate of 3 ml/kg/h from the start to the end of surgery. |
適格基準
| 研究の対象となる年齢 | 3 Years に 3 Years |
| 研究に適格な性別 | All |
| 健康なボランティアを受け入れる | はい |
| 基準 | Inclusion Criteria: - scheduled for repair of penile hypospadias with American Society of Anaesthesiologists' physical status of class I-II. Exclusion Criteria: - Patients with pulmonary, cardiovascular, or hematological disorders or a family history of allergy to local anesthetics or lung disease |
結果
主な結果の測定
1. volume overload using lung ultrasound [intraoperative duration that is approximately 110 minutes.]
volume overload using lung ultrasound according to The mean number of B-lines detected on the ultrasound image
