Study of Obesity Control by Astragalus and Notoginseng Extrats
キーワード
概要
説明
Obesity refers to the body due to physiological or biochemical function of the change caused by excessive accumulation of body fat, resulting in weight gain. Hence, the aim of this study was to evaluate the effects of the Astragalus and Notoginseng extrats on obesity control by a randomized double-blind and crossover human trial. Subjects with simple obesity (body mass index (BMI) ≥ 27 or body fat ≥ 30%) ingested 5 extrats (n = 19) capsules or placebo (n = 19) perday for 12 weeks of a stage. Anthropometric measurements (body weight, body fat, blood pressure) and blood biochemical markers including fasting blood glucose (FBG), albumin, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, creatinine (Cr), blood urea nitrogen (BUN), AST, ALT were examined every six weeks.
日付
| 最終確認済み: | 11/30/2019 |
| 最初に提出された: | 08/28/2018 |
| 提出された推定登録数: | 08/28/2018 |
| 最初の投稿: | 08/30/2018 |
| 最終更新が送信されました: | 12/12/2019 |
| 最終更新日: | 12/15/2019 |
| 実際の研究開始日: | 09/30/2016 |
| 一次完了予定日: | 07/31/2017 |
| 研究完了予定日: | 09/30/2017 |
状態または病気
介入/治療
Dietary Supplement: InnoSlim
Dietary Supplement: Placebo
段階
アームグループ
| 腕 | 介入/治療 |
|---|---|
| Active Comparator: InnoSlim Subjects ingested 2 capsules InnoSlim® (Experimental group) in the morning and 3 capsules in the evening (5 capsules/d) for 12 weeks of a stage. | Dietary Supplement: InnoSlim Subjects ingested 2 capsules (Experimental group) in the morning and 3 capsules in the evening (5 capsules/d) for 12 weeks of a stage. Anthropometric measurements such as body weight, body fat, waistline, hipline, blood pressure (systolic blood pressure [SBP] and diastolic blood pressure [DBP]) and blood biochemical parameters including FBG, albumin, TC, TG, HDL-C, LDL-C, Cr, BUN, AST and ALT were measured every six weeks. |
| Placebo Comparator: Placebo Subjects ingested 2 capsules placebo (Control group) in the morning and 3 capsules in the evening (5 capsules/d) for 12 weeks of a stage. | Dietary Supplement: Placebo Subjects ingested 2 capsules placebo in the morning and 3 capsules in the evening (5 capsules/d) for 12 weeks of a stage. Anthropometric measurements such as body weight, body fat, waistline, hipline, blood pressure (systolic blood pressure [SBP] and diastolic blood pressure [DBP]) and blood biochemical parameters including FBG, albumin, TC, TG, HDL-C, LDL-C, Cr, BUN, AST and ALT were measured every six weeks. |
適格基準
| 研究の対象となる年齢 | 20 Years に 20 Years |
| 研究に適格な性別 | All |
| 健康なボランティアを受け入れる | はい |
| 基準 | Inclusion Criteria: - Body mass index (BMI) ≥ 27 or body fat ≥ 30%; - No history of serious diseases associated with heart, liver, kidney, endocrine systems or other organs; - No drugs consumption. Exclusion Criteria: - BMI >35; - Alcoholic; - US-controlled diabetics; - Stoke in past one year; - High blood pressure; - Mental diseases or melancholia; - Pregency or breast-feeding a child. |
結果
主な結果の測定
1. The changes of body weight and BMI of the subjects. [12 weeks]
二次的な結果の測定
1. The changes of triglyceride (TG) of the subjects [12 weeks]
