Trimethylamine N-oxide in Myocardial Infarction
キーワード
概要
説明
This study includes patients with their first STEMI. The investigators measure plasma TMAO levels using the frozen plasma at the onset of STEMI and 10 months later (the chronic phase). To assess plaque progression, residual SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) score and chronic-phase SYNTAX score are measured. After the chronic-phase assessment of TMAO and SYNTAX score, patients are followed for cardiovascular events including death, myocardial infarction, ischemic stroke, and unstable angina pectoris with coronary revascularization.
日付
| 最終確認済み: | 12/31/2017 |
| 最初に提出された: | 01/24/2018 |
| 提出された推定登録数: | 01/24/2018 |
| 最初の投稿: | 01/31/2018 |
| 最終更新が送信されました: | 01/30/2018 |
| 最終更新日: | 02/04/2018 |
| 実際の研究開始日: | 12/31/2006 |
| 一次完了予定日: | 12/31/2017 |
| 研究完了予定日: | 12/31/2017 |
状態または病気
段階
適格基準
| 研究の対象となる年齢 | 20 Years に 20 Years |
| 研究に適格な性別 | All |
| サンプリング方法 | Non-Probability Sample |
| 健康なボランティアを受け入れる | はい |
| 基準 | Inclusion Criteria: - Patients who admitted to the Yokohama City University Medical Center with the diagnosis of their first STEMI and who underwent primary percutaneous coronary intervention within 12 hours after onset and received follow-up coronary angiogram 10 months after the index intervention. Exclusion Criteria: - none |
結果
主な結果の測定
1. MACE [6 years]
二次的な結果の測定
1. Coronary plaque progression [10 months]
