Planta Medica 2011-Nov
Flavonoids from the roots of Campylotropis hirtella.
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概要
Eight new flavonoids, including three pterocarpene derivatives, hirtellanines C-E, two flavanones, hirtellanines F and G, three isoflavanones, hirtellanines H-J, as well as four known compounds were isolated from the roots of Campylotropis hirtella. The structures of the new compounds were elucidated by spectroscopic analyses, including 2D-NMR techniques. Pharmacological investigation indicated that the new compounds, particularly hirtellanines D and G, possessed potent immunosuppressive activities and low relative cytotoxicities.
