Fitoterapia 2010-Sep
Fuscacarpans A-C, new pterocarpans from the stems of Erythrina fusca.
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概要
Chemical investigation of the stems of Erythrina fusca Lour. led to the isolation of three new pterocarpans, named fuscacarpans A-C (1-3), together with fourteen known compounds, sandwicensin (4), erythribyssin A (5), erythrabissin I (6), demethylmedicarpin (7), eryvarin D (8), erypoegin I (9), hydroxycristacarpone (10), orientanol A (11), scandenone (12), genistein (13), liquiritigenin (14), isoliquiritigenin (15), vestitone (16) and 3,7,4'-trihydroxyflavone (17). Structures 1-3 were elucidated by spectroscopic and chemical methods. The isolates were evaluated for antibacterial, antiplasmodial and cytotoxic activities.