Japanese
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 2007-Feb

[The analgesic mechanism of total flavone of rhododendron].

登録ユーザーのみが記事を翻訳できます
ログインサインアップ
リンクがクリップボードに保存されます
Xiao-ping Song
Zhi-wu Chen
Jian-hua Zhang
Bo Ding

キーワード

概要

OBJECTIVE

To study the analgesic mechanisms of total flavone of rhododendron (TFR).

METHODS

On hot-plate test in mice, the changes of the latencies of licking paws were observed after drug administration. Meanwhile, the contents of nitric oxide (NO) and prostaglandin E2 (PGE2 ) in the mice serum and cereburum were measured by Griss reaction and spectrophotomtry methods, respectively. The expression of inducible nitricoxide synthase (iNOS) in mices was detected by the reverse transcription -porymerse chain reaction (RT-PCR) technique.

RESULTS

TFR 100, 200 mg/kg ig remarkably prolonged the latencies of licking paws in mice. 100 mg/kg TFR ig significantly increased the mice serum NO content, and 200 mg/kg TFR ig markedly increased the NO content as well as promoted the iNOS mRNA expression in mice cerebrum. TFR 50,100,200 mg/kg ig significantly reduced the contents of PGE2 in mice cerebrum and 200 mg/kg TFR ig remarkably reduced the PGE2 contents in mice serum.

CONCLUSIONS

Analgesic effects of TFR may be related to promoting the release of NO and increasing expression the of iNOS as well as inhibiting the production of PGE2.

Facebookページに参加する

科学に裏打ちされた最も完全な薬草データベース

  • 55の言語で動作します
  • 科学に裏打ちされたハーブ療法
  • 画像によるハーブの認識
  • インタラクティブGPSマップ-場所にハーブをタグ付け(近日公開)
  • 検索に関連する科学出版物を読む
  • それらの効果によって薬草を検索する
  • あなたの興味を整理し、ニュース研究、臨床試験、特許について最新情報を入手してください

症状や病気を入力し、役立つ可能性のあるハーブについて読み、ハーブを入力して、それが使用されている病気や症状を確認します。
*すべての情報は公開された科学的研究に基づいています

Google Play badgeApp Store badge