arteannuin/悪性腫瘍

It has been found in recent years that Artesunate (Art), a water soluble derivative of arteannuin, mainly previously used for its anti-malarial activity, has some other effects, e.g. it could act as an anti-tumor agent by way of inducing cell apoptosis, antagonizing angiogenesis, reversing

OBJECTIVE To investigate the anticancer activity of dihydroartemisinin (DHA), a derivative of antimalaria drug artemisinin in a panel of human ovarian cancer cell lines. METHODS Cell growth was determined by the MTT viability assay. Apoptosis and cell cycle progression were evaluated by a DNA

The cytotoxic activity of nine terpenoids and flavonoids isolated from Artemisia annua was tested in vitro on several human tumor cell lines. These compounds are artemisinin, deoxyartemisinin, artemisinic acid, arteannuin-B, stigmasterol, friedelin, friedelan-3 beta-ol, artemetin, and quercetagetin

BACKGROUND In addition to recognized antimalarial effects, Artemisia annua L. (Qinghao) possesses anticancer properties. The underlying mechanisms of this activity are unknown. The aim of our experiments was to investigate the effects of distinct types of compounds isolated from A. annua on the