3 結果
The study proposes two specific aims Aim 1 will determine if blocking enteric neuronal signaling will alter: a) circulating levels of nutrient substrates and secretion of hormones that regulate nutrient metabolism; and b) glucose and fatty acid absorption, production, and utilization.
Obese (BMI =
1. BACKGROUND AND RATIONALE:
Current obesity prevention emphasizes increasing physical activity and a low-fat, calorie restricted diet to produce a negative caloric balance. Caloric restriction is associated with decreases in energy expenditure. The other mainstay of obesity prevention increasing
The early management of type 2 diabetes usually consists of education related to lifestyle changes especially as 80 to 90% of people with type 2 diabetes are obese. Obesity worsens the metabolic and physiological abnormalities associated with diabetes particularly hyperglycaemia (raised blood