The present invention provides curcumol derivatives of the following formula (I) or pharmaceutical acceptable salts thereof: ##STR00001## wherein, Y is selected from the group consisting of .dbd.CHR.sup.2, --CH.sub.2R.sup.2, .dbd.O, ##STR00002## --OH or --OR.sup.1;R.sup.1 is selected from H, R, RCO or HO.sub.3S; and R is selected from the group consisting of H; saturated or unsaturated linear C.sub.1-10 hydrocarbon group and the like; R.sup.2 is selected from the group consisting of F; Cl; Br; I; H; --OH; --OR; --HSO.sub.3 and the like; with the proviso that both R.sup.1 and R.sup.2 are not H. The present invention also provides anti-tumor or antiviral pharmaceutical compositions comprising said derivatives or pharmaceutical acceptable salts thereof. The present invention further provides the use of said derivatives or pharmaceutical acceptable salts thereof in the preparation of a medicament for prophylaxis and/or treatment tumor or an antiviral medicament.

curcumol/悪性腫瘍

Curcumol derivatives, the compositions containing the said derivatives, and the use of the same in the manufacture of medicaments

科学に裏打ちされた最も完全な薬草データベース