diosbulbin d/カシュウイモ

OBJECTIVE To study the chemical constituents in the tubers of Dioscorea bulbifera. METHODS Compounds were isolated and purified with silica gel, ODS and Sephadex LH-20 column chromatography, their structures were determined by using spectroscopic methods including MS and NMR. RESULTS Fourteen

Numerous furanoids have been reported to be toxic, and many of them were found in herbal medicines. Toxicities of furanoids are suggested to result from the generation of cis-enedials via biotransformation. The detection of the electrophilic metabolic intermediates is a challenge. Earlier, we