ergocristine/tachycardia

(1) The action of ergocristine at alpha-adrenoceptors was studied in vivo in the pithed rat, and in vitro on the rat isolated vas deferens. (2) In the pithed rat, the pressor response to ergocristine was reduced competitively by yohimbine, but not by prazosin. (3) Ergocristine decreased the

A sample of ergot from meadow grass collected in the south-western part of Norway was examined for alkaloids and dosed orally to four lambs about 10 months old. Sclerotia were dosed at a rate of 0.12-0.75 g per kg body weight per day for 4-27 days. The concentration of total alkaloids in the