erythrina subumbrans/lectin

The study reports on the effect of 6 antimalarial drugs on red cell agglutination by Erythrina lithosperma. Phaseolus vulgaris and Ulex europaeus lectins. Some drugs inhibited agglutination while others potentiated it. Possible causes have been discussed.

A lectin obtained from seeds of Erythrina lithosperma detects a new specificity, called LH, on the human red blood cell membrane. Family investigations show conclusively that the specificity is under autosomal genetic control, with the gene determining the LH- type being dominant over its allele for