7 結果
Ginkgolic acid (15:1) is a major toxic component in extracts obtained from Ginkgo biloba (EGb) that has allergic and genotoxic effects. This study is the first to explore the hepatotoxicity of ginkgolic acid (15:1) using a NMR (nuclear magnetic resonance)-based metabolomics approach in combination
A Ginkgo biloba L. fruit extract was prepared and purified. Three groups of guinea pigs were sensitized to the crude extract, anacardic acids 1, and cardanols 2 respectively, using the FCAT method, and the fourth group to urushiol using the epicutaneous route. Each group was tested for reaction to
BACKGROUND
Ginkgo biloba possesses fruits that have caused numerous cases of allergic contact dermatitis. Low amounts of the ginkgolic acids occur in the leaves as well.
OBJECTIVE
Leaf extracts are used to treat cerebrovascular and peripheral vascular disorders. The question arises whether skin
Ginkgo biloba leaf extract contains many health beneficial active ingredients. However, ginkgolic acid, one of the major components found in G. biloba extract, may cause serious allergic and toxic side effects to the living organisms. The purpose of this study is to immobilize the Ginkgolic acid and related alkylphenols constitute major components of the lipid fraction of the fruit pods of Ginkgo biloba L. In addition, this class of substances is present in Ginkgo leaves which are widely used to prepare extracts for the treatment of peripheral or cerebral circulatory
Allergic reactions due to contact with different parts of the ancient tree Ginkgo biloba L. have repeatedly been reported. Provocation tests in patients and animal experiments have identified alkylphenols such as ginkgolic acids as causative constituents. Leaf extracts from Ginkgo are widely used to
The new age of nutraceuticals is now embracing the centuries old herbal extract of Ginkgo biloba (Mantissa Plantarum Altera, 1771, Ginkgoceae). The standardized preparation of the Ginkgo leaf extract (EGb 761) contained 2 main bioactive constituents, flavonoid glycosides (24%) and terpene lactones