glomus tumor/セロトニン

Glomus tumors arise in the chemical receptors of vessels in the tympanic and jugular regions. Clinical signs depend on location, the structures invaded and a tumor's ability to secrete active amines and peptides. A 44-year-old woman was scheduled for excision of a serotonin-secreting tympanic glomus

Substance P (SP), S-100 protein, methionine-enkephalin, serotonin and myelin basic protein were studied in two solitary glomus tumours of the skin by peroxidase-antiperoxidase immunohistochemistry. Multiple SP-containing nerve fibres were distributed in the parenchyma of the tumour among

Glomus tumors arising in the temporal bone are now recognized as being part of the diffuse neuroendocrine system. Material from 12 glomus tumors was studied by means of electron microscopic and immunohistochemical techniques to determine whether there was an association between tumor size, patient

The genes responsible for hereditary paragangliomas (glomus tumors, MIM No. 168000) have been mapped to two distinct loci on the long arm of chromosome 11. Most of the informative families appear to be linked to the distal locus on chromosome 11q23 (PGL1), which has been previously confined to a

Eight cases of glomus tumor (chemodectoma) are reported. All the patients were women aged 46-55 years with complaints of noise in the ears, diminished hearing, pains on the side of the tumor. Some of the patients had ear discharge. Neurinoma, ear polyp, hemangioma and ceruminoma were rejected at