The effect of oral administration of an aqueous extract of the bark of Helicteres isora was investigated on blood glucose and plasma antioxidant status in streptozotocin (STZ) induced diabetic rats. The study was also undertaken to evaluate the role of hepatic enzymes in experimental diabetes. Oral
BACKGROUND
We characterized saponins as active constituents from traditionally used antidiabetic plant Helicteres isora.
OBJECTIVE
To evaluate the changes in the gene expression of the glucose and lipid metabolism regulating genes in C57BL/KsJ-db/db mice.
METHODS
C57BL/KsJ-db/db mice were divided