6 結果
[3H]Choline was taken up by tissue slices of the cestode Hymenolepis diminuta by sodium-dependent and sodium-independent mechanisms. The sodium-dependent uptake was saturable, against an apparent concentration gradient, and by analysis of the kinetics of uptake could be delineated into a
The effect of high potassium depolarization on the release of exogenously supplied [3H]glutamate and endogenous glutamate from tissue slices of the cestode Hymenolepis diminuta was examined. Increasing concentrations of potassium stimulated the release of radiolabel from tissues preloaded with
1. Mitochondria from adult Hymenolepis diminuta displayed a membrane-associated, rotenone-sensitive NADH oxidase and NADH-dependent fumarate reductase system. 2. Both the H. diminuta oxidase and fumarate reductase were relatively insensitive to antimycin A. potassium cyanide and sodium azide, at
Radiolabelled choline was taken up by tissue slices of the cestode Hymenolepis diminuta by a sodium-dependent and a sodium-independent mechanism. The sodium-dependent uptake was saturable, against a concentration gradient, displayed structural specificity, and was inhibited, in part, by
A simple and convenient in vitro technique is described for the screening of compounds for action against Hymenolepis nana and probably many other intestinal worms. The results obtained from this test are in broad agreement with the findings of clinical experience and of a small series of in vivo