OBJECTIVE
To evaluate the hepatoprotective activity of ethanolic and aqueous extract of stems of Leptadenia reticulata (Retz.) Wight. and Arn. in carbon tetrachloride (CCl(4))-induced hepatotoxicity in rats.
METHODS
The toxicant CCl(4) was used to induce hepatotoxicity at a dose of 1.25 ml/kg as 1 :
Materials and methods: Various aqueous extracts were prepared from this plant and preadministered per os to albino mice 3 h before APAP administration, once daily for one week. Animals from the normal group were given only distilled water