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lirioresinol/モクレン属

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記事臨床試験特許
4 結果

[Biologically active lignins from Magnolia biondii Pamp].

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Guided by PAF induced platelet aggregation, six active lignins were isolated from the flower buds of Magnolia biondii and identified as fargesin, demethoxyaschantin, aschantin, pinoresinol dimethyl ether, magnolin, lirioresinol-B dimethyl ether. The 13CNMR and CD data were reported and the

[Lignans from flower buds of Magnolia biondii].

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The present study aims to investigate the lignans from the flower buds of Magnolia biondii. The isolation and purification of the compounds were performed by column chromatographies on Diaion HP-20, silica gel, and Sephadex LH-20, combined with semi-preparative HPLC. Their structures were elucidated

5-lipoxygenase-inhibitory constituents from Schizandra fructus and Magnolia flos.

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In order to establish the antiallergic properties of Schisandra fructus and Magnolia flos, several compounds isolated from these plants were tested for 5-lipoxygenase (5-LOX) inhibitory activity in vitro, for the first time. The compounds including schizandrins, schisandrols, gomisins, fargesin,

Isolation and identification of inhibitory compounds on TNF-alpha production from Magnolia fargesii.

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Three TNF alpha-inhibitory lignans were isolated from the flower buds of Magnolia fargesii through bioassay-guided isolation. They were identified as eudesmin, magnolin and lirioresinol-B dimethylether on the basis of their spectroscopic data. All three lignans showed inhibitory effects on TNF-alpha
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