micromelum falcatum/二酸化ケイ素

OBJECTIVE To study the chemical constituents from ethyl acetate extract of Micromelum falcatum. METHODS The constituents were separated and purified by silica gel, Sephadex LH-20 and HPLC. Their structures were elucidated by spectral analysis (NMR, MS). RESULTS Ten compounds were isolated and

Extracts of Micromelum integerrimum (Buch.-Ham. ex Coleb.) M. Roem. were fractionated based on in vivo activity in mice in the P-388 lymphocytic leukemia system. Activity in ethanol extracts was concentrated in the chloroform partition fraction, which was further resolved by chromatography on silica

A new benzene derivative microintegerrin C (1) and a new norsesquiterpenoid microintegerrin D (2), along with six known compounds (3-8), were isolated and identified from stems and leaves of Micromelum integerrimum by various chromatographies such as silica gel, Sephadex LH-20, RP-18 column

OBJECTIVE To investigate the chemical and bioactive constituents from the stems and leaves of Micromelum integerrimum. METHODS The chemical constituents were isolated and purified by silica gel, Sephadex LH-20, and HPLC. Their structures were mainly elucidated on the basis of extensive 1D- and