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octanal/inflammation

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5 結果

Octanal-induced inflammatory responses in cells relevant for lung toxicity: expression and release of cytokines in A549 human alveolar cells.

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Inhalation is an important route of aldehyde exposure, and lung is one of the main targets of aldehyde toxicity. Octanal is distributed ubiquitously in the environment and is a component of indoor air pollutants. We investigated whether octanal exposure enhances the inflammatory response in the

Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-Ay mice.

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When the microfloral composition deteriorates, it triggers low-level chronic inflammation associated with several lifestyle-related diseases including obesity and diabetic mellitus. Fecal volatile organic compounds (VOCs) have been found to differ in gastrointestinal diseases as well as intestinal

Formation of potentially toxic carbonyls during oxidation of triolein in the presence of alimentary antioxidants.

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UNASSIGNED A relation between oil uptake and cancer as well as induction of hepatic inflammation was shown earlier. It is discussed that the main oil oxidation products-hydroperoxides and carbonyls-might be the reason for the mentioned diseases. In this manuscript quantitative determination of

Possible role of aldehydic lipid peroxidation products as chemoattractants.

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Previous studies showed that the lipid peroxidation product 4-hydroxy-trans-2-nonenal (HNE) stimulates the rat neutrophil oriented migration in vitro within a micromolar range. Its effect is weak with respect to other known chemoattractants, but highly significant on the basis of a two-way analysis

Activation of olfactory receptors on mouse pulmonary macrophages promotes monocyte chemotactic protein-1 production.

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BACKGROUND Emerging evidence suggests that non-olfactory tissues and cells can express olfactory receptors (ORs), however, the exact function of ectopic OR expression remains unknown. We have previously shown in mouse models that a unique cooperation between interferon-γ (IFN-γ) and
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