ocular hypertension/アルブミン

OBJECTIVE To compare plasma cortisol binding as well as total plasma cortisol, free cortisol and percent free cortisol in normals, ocular hypertensives and primary high pressure open-angle glaucomas. METHODS Blood samples were obtained on outpatient visits of 18 normals, 19 ocular hypertensives and

To analyze the responses of different retinal ganglion cell (RGC) types to acute ocular hypertension (AOH) and intravitreal administration of brain-derived neurotrophic factor (BDNF). In adult albino rats, the anterior chamber of the left eye was cannulated with a needle connected to a saline

BACKGROUND This study was carried out in order to improve the understanding of the pathogenesis of uveitic glaucoma. METHODS Uveitis was induced in 48 Lewis rats by S-antigen injection. Intraocular pressure (IOP) was measured by Tono-Pen-2 daily for 24 days in 16 animals. Histopathology was

SR121463 is a selective, orally active, non-peptide antagonist of vasopressin (AVP) V(2) receptors with powerful aquaretic properties in various animal species and humans. SR121463 belongs to a new class of drugs, called aquaretics, which are capable of inducing free-water excretion without

Misoprostol, a prostaglandin E1 analog, is a racemate of four stereoisomers. On administration it rapidly de-esterifies to its active form, misoprostolic acid. Misoprostolic acid is 85% albumin bound and has a half-life of approximately 30 minutes. It is excreted in urine as inactive metabolites. No

Conjunctival inflammation disturbs the blood-tear barrier and thus affects the tear film stability and composition. We aimed to develop a non-invasive and reliable method to induce conjunctivitis in dogs, a large animal model for translational work on ocular surface disease in humans. Six beagle