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oleandomycin/inflammation

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The effect of tetracycline and oleandomycin on the complement titer, lysozyme content, serum bactericidal properties and presence of specific antibiotic antibodies in the blood serum was studied. The latter were shown with the Hoigné reaction under conditions of aseptic inflammation caused against

[Demonstration of the anti-inflammatory power and research on the mode of action of triacetyl-oleandomycin (T.A.O.) in asthma].

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[OLEANDOMYCIN IN THE TREATMENT OF INFLAMMATORY LUNG DISEASES].

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[Antibiotic sensitivity of Haemophilus influenzae isolated from patients with inflammatory lung diseases].

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In 1980-1986 the sensitivity of 2,045 H. influenzae strains isolated from the bronchial contents of patients with inflammatory lung diseases were studied. This study revealed that 60-80% of H. influenzae cultures circulating in Leningrad were sensitive to tetracyclin, chloramphenicol and

[Antibacterial preparation sensitivity of staphylococcal strains isolated from patients with inflammatory diseases of the male genitalia].

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The data on the drug sensitivity of 517 staphylococcal strains isolated from the prostate secretion, separate contents of the right and left seminal vesicles, ejaculate and urine of 250 male patients with inflammatory diseases of the genitalia are presented. It is shown that aminoglycoside

Impact of stereochemistry on the biological activity of novel oleandomycin derivatives.

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A set of 8-methylene-, 8-methyl-, and 8-methyl-9-dihydro-oleandomycin derivatives having different combinations of stereochemistries at positions C-8 and/or C-9 have been prepared in a chemoselective and stereoselective manner and tested in vitro for antibacterial activity and inhibition of IL-6

Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium.

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Exacerbations of asthma and COPD are triggered by rhinoviruses. Uncontrolled inflammatory pathways, pathogenic bacterial burden and impaired antiviral immunity are thought to be important factors in disease severity and duration. Macrolides including azithromycin are often used to treat the above

[Antibiotic sensitivity of Streptococcus pneumoniae strains isolated from the bronchial contents of patients with inflammatory lung diseases].

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The study of the sensitivity of 2681 pneumococcal strains to antibiotics, carried out in 1976-1982, demonstrated that most of these strains circulating in Leningrad were sensitive to penicillin, levomycetin, erythromycin and oleandomycin. Penicillin-resistant pneumococcal strains were found to

Biosynthesis of Polyketides in Streptomyces.

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Polyketides are a large group of secondary metabolites that have notable variety in their structure and function. Polyketides exhibit a wide range of bioactivities such as antibacterial, antifungal, anticancer, antiviral, immune-suppressing, anti-cholesterol, and anti-inflammatory activity.

Molecular identification and histopathological study of natural Streptococcus agalactiae infection in hybrid tilapia (Oreochromis niloticus).

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OBJECTIVE The main objective of this study was to emphasize on histopathological examinations and molecular identification of Streptococcus agalactiae isolated from natural infections in hybrid tilapia (Oreochromis niloticus) in Temerloh Pahang, Malaysia, as well as to determine the susceptibility

[Comparative antibiotic sensitivity characteristics of the staphylococci isolated from ambulatory and hospitalized patients].

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Sensitivity of staphylococci isolated from the pathological material of outpatients with purulent inflammatory infections and inpatients was studied with respect to 10 antibiotics. The agar diffusion method with standard paper discs impregnated with the antibiotics was used. It was shown that the

[Interrelation of the antibiotic sensitivity (resistance) of staphylococci, clinical forms of the infection and production of protein A].

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Two hundred and thirty-two strains of Staph. aureus isolated from patients with staphylococcal infections were studied. The strains were isolated from the blood of patients with sepsis, from the purulent foci on the skin and in the subcutaneous fat, from the nasopharyngeal mucosa of patients with

Demonstration of non-inferiority of a novel combination intramammary antimicrobial in the treatment of clinical mastitis.

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OBJECTIVE To test the non-inferiority of a novel combination intramammary product containing penicillin and cloxacillin to a reference intramammary product containing oxytetracycline, oleandomycin, neomycin and prednisolone with regard to bacteriological cure and clinical cure. METHODS Clinical

[Puerperal mastitis].

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The puerperal mastitis is a staphylococcal infection of the lactating mamma cumulating during the third and fourth week after delivery. It is seen three times as often after hospital than after house delivery, and it is also more frequent with primiparae than with multiparae. The infection is caused
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