peliosis hepatis/amyloid

Sinusoidal alterations unrelated to primary hepatocellular damage present without characteristic clinical findings and in these cases the liver biopsy is particularly important. Capillarization of sinusoids is characterized by closing of fenestration, formation of a basal membrane and by the

A 38 year old woman presented portal hypertension and proteinuria. Liver biopsy showed peliosis hepatis with non amyloid deposits, reactive with anti-kappa antibody by immunofluorescence, along the sinusoids and in the Disse spaces. There are identical deposits along glomerular and tubular basement

BACKGROUND A spontaneous hepatic haemorrhage (SHH) is a rare condition that presents acutely to both hepatobiliary and general surgeons. Management of the condition is challenging because of the emergent presentation requiring immediate intervention, the presence of underlying chronic liver disease