phytolaccagenin/ヤマゴボウ属

Radix Phytolaccae (the dried root of Phytolacca acinosa Roxb. or Phytolacca americana L.) is widely used in East Asian countries for the treatment of inflammation-related diseases. The active component of Radix Phtolaccae is Phytolcaccagenin a triterpenoid saponin. Phytolcaccagenin has

In leaves, roots and calli of P. dodecandra we found two 28,30-dicarboxyolean-12-enes and their glycosides in addition to the hitherto known four 28-monocarboxyolean-12-enes on which the chemotaxonomy was based. Therefore, P. dodecandra can no longer be considered as chemotaxonomically different

A saponin-rich extract of Phytolacca dioica L. berries, its acid hydrolysate, and its major aglycone, phytolaccagenin, were assayed for antifungal activity against ATCC standard cultures of Candida albicans and Cryptococcus neoformans, and against clinical isolates of these fungi. The activity of

The methanolic extract of the berries of Phytolacca tetramera, an Argentinean species submitted to a great anthropic impact, and therefore in critic risk of extinction, not previously studied, showed antifungal activity against opportunistic pathogenic fungi. Through fractionation of the extract

The investigation of the hydrolysed aqueous methanolic extract from the leaves of PHYTOLACCA ACINOSA Roxb. resulted in the isolation of phytolaccagenin ( 1) besides a new pentacyclic triterpenoid which was identified as 2beta,3beta-dihydroxy-23,30-dimethoxycarbonyl-28-carboxy-olean-12-ene =

A new water-soluble saponin (esculentoside H) has been isolated from the roots of Phytolacca esculenta and identified as 3-O-[beta-D-glucopyranosyl-(1----4)-beta-D-xylopyranosyl]-28-O-beta-D- glucopyranosyl phytolaccagenin.

Two triterpenoidal saponins having phytolaccagenin as the aglycone were isolated from the roots of Phytolacca esculenta (Phytolaccaceae). The structures of two new saponins, esculentoside I and esculentoside N, were established to be 3-O-[beta-D-glucopyranosyl-(1----4)-beta-D-

Phytolacca acinosa is an herb for treatment of ascites and tumor. Two forms of phytolacca acinosa, i.e. raw and vinegar-processed herb, have been used in clinic. However, pharmacokinetic difference between the two forms of phytolacca acinosa has not been fully understood. Herein, a comparative

In Phytolaccaceae family, Phytolacca americana L. (American pokeweed) and P. esculenta Van Houtte (Chinese pokeweed) are the two representative species among the genus. Pokeweeds have triterpenoid saponins as toxic compounds in every part of the plant. The saponins phytolaccoside A, B, D, E, and G

Follicular atresia is one of the main processes for the loss of granulosa cells and oocytes from the mammalian ovary and any impairment to premature ovarian failure. Large numbers of studies have demonstrated that granulosa cell apoptosis causes follicular atresia, yet the rescue of these cells

Background: Esculentosides and related phytolaccosides form a group of oleanene-type saponins isolated from plants of the Phytolaccaceae family, essentially Phytolacca esculenta, P. americana and P. acinosa. This chemical family offers a