3 結果
Most of the breast cancer deaths occur when cancer cells depart from their tumour of origin and spread systemically and colonise distant organs. The present study was to find out whether punarnavine, the quinolizidine alkaloid, with already proven antimetastatic effect on spontaneous B16F10
The alkaloid Punarnavine isolated from the plant Boerhaavia diffusa Linn. was studied for its anti-metastatic activity using B16F-10 melanoma cells in C57BL/6 mice. Administration of Punarnavine (40mg/kg body weight) prophylactically (95.25%), simultaneously (93.9%) and 10 days after tumor
Effect of Punarnavine on the cell-mediated immune (CMI) response in metastatic condition was studied using C57BL/6 mice model. Administration of Punarnavine enhanced Natural Killer (NK) cell activity, antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent complement mediated