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quassin/quassia

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The effect of Quassia amara extract and two isolated compounds from the extract, quassin and 2-methoxycathine-6-one on haematological parameters was studied in rats. All doses of the extract and those of the quassin significantly increased red blood cell count, packed cell volume and haemoglobin

Antifertility activity of Quassia amara: quassin inhibits the steroidogenesis in rat Leydig cells in vitro.

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The crude methanol extract of the stem wood of Quassia amara L. inhibited both the basal and LH-stimulated testosterone secretion of rat Leydig cells in a dose-dependent fashion. Fractionation of the extract by chromatography gave quassin (1) and 2-methoxycanthin-6-one (2); compound 1 proved to be

Larvicidal efficacy of Quassin against Culex quinquefasciatus.

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Crushed aqueous extracts of leaf, wood, bark and flowers of Quassia amara showed antilarval activity against C quinquefasciatus. Quassin has been identified to be the antilarval principle present in this plant and was effective against mosquito larvae at a concentration of 6 ppm. Quassin was present

Effect of quassin on the metabolism of catecholamines in different life cycle stages of Culex quinquefasciatus.

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Quassin, a mosquito larvicide isolated from Quassia amara, inhibits tyrosinase activity in the larvae of Culex quinquefasciatus. Since tyrosinase is directly involved in sclerotisation of the cuticle, it is suggested that quassin, as a larvicide, inhibits development of the cuticle. In presence of

Reproductive activities of female albino rats treated with quassin, a bioactive triterpenoid from stem bark extract of Quassia amara.

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To evaluate the effect of quassin on female reproductive functions, 42 albino rats (35 females and 7 males) were used. The female albino rats were divided into seven groups of five rats each. Group I served as the control group and received distilled water while Groups II, III and IV rats were

Plasmodium falciparum: in vitro interaction of quassin and neo-quassin with artesunate, a hemisuccinate derivative of artemisinin.

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Quassia amara L. (Family Simaroubaceae) is known to have several medicinal properties including the activity against malaria. An HPLC method was employed for purification of the biologically active quassinoids; quassin (Q) and neo-quassin (NQ), further characterized by MALDI-TOF analyses. Purified

Liquid chromatography electrospray ionization tandem mass spectrometric determination of quassin and neoquassin in fruits and vegetables.

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Quassia amara wood chips are used by organic farmers as a valid alternative to synthetic insecticides. The powder of Q. amara contains high levels of quassin, neoquassin and picrasinoside B. In this study we developed a liquid chromatography mass spectrometry method for the rapid and accurate
Alcohol Denat. is the generic term used by the cosmetics industry to describe denatured alcohol. Alcohol Denat. and various specially denatured (SD) alcohols are used as cosmetic ingredients in a wide variety of products. Many denaturants have been previously considered, on an individual basis, as

[Development of a Novel Method for Quantifying Quassin and Neoquassin in Jamaica Quassia Extracts Using the Molar Absorption Coefficient Ratio].

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A novel HPLC-based method employing molar absorption coefficient ratios to 4-hydroxybenzoic acid (4HBA) was developed for the determination of quassin and neoquassin in Jamaica quassia extract, which is used as a food additive in Japan. Based on comparisons of quantitative NMR (qNMR) spectra and

Antifertility activity of Quassia amara in male rats - in vivo study.

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The crude methanol extract of the stem wood of Quassia amara. L. (A-1) significantly caused a reduction in the weight of the testis, epididymis and seminal vesicle, but an increase in that of the anterior pituitary gland. Epididymal sperm counts, serum levels of testosterone, luteinizing hormone

2-Methoxycanthin-6-one: A New Alkaloid from the Stem Wood of Quassia amara.

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A new alkaloid, 2-methoxycanthin-6-one ( 1) has been isolated from the methanol extract of the stem wood of QUASSIA AMARA. In addition quassin ( 6) was also isolated. The structure of 1 was determined by spectroscopic methods.

Antiulcerogenic effects and possible mechanism of action of Quassia amara (L. Simaroubaceae) extract and its bioactive principles in rats.

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The effects of Quassia amara extract (Q. amara) and its bioactive principles-quassin and 2-methoxycanthin-6-one on gastric ulceration were studied in albino rats. Q. amara (200-800 mg/kg p.o.; 5-20 mg/kg i.p) and 2-methoxycanthin-6-one (12.5, 25.0 and 50.0 mg/kg p.o; 1, 2 and 4 mg/kg i.p) but not

[Analysis of constituents in Jamaica quassia extract, a natural bittering agent].

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Jamaica quassia extract, a natural bittering agent, is described as "a substance extracted from bark of Jamaica quassia (Quassia excelsa Sw.)" in the List of Existing Food Additives in Japan. The constituents in Jamaica quassia extract product were investigated as a part of an ongoing study to

[Examination of original plant of Jamaica quassia extract, a natural bittering agent, based on composition of the constituents].

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Jamaica quassia extract is a natural bittering agent used as a food additive in Japan. The main constituents of the extract have already been reported to be quassin and neoquassin. In this study, the differences in composition of the constituents among four Jamaican quassia extract products were

Antiviral activity of simalikalactone D, a quassinoid from Quassia africana.

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After removing lipophilic material, the ground root bark of Quassia africana Baill. (Simaroubaceae) was extracted with ethanol 95 %. Partitioning between chloroform, ethyl acetate and water yielded three crude extracts. Pronounced activities were shown by the chloroform and ethyl acetate crude
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