rectovaginal fistula/headache

OBJECTIVE This report stresses the importance of local complications caused by ergotamine abuse for the treatment of migraine headaches. METHODS We present an unusual case of a complex rectovaginal fistula (RVF) caused by long-term ergotamine suppository abuse. RESULTS A 39-year-old female was

We observed a rectovaginal fistula in 2 patients who had applied ergotamine suppositories against migraine headaches. The local effect of ergotamine on the rectum mucosa as well as the higher systemic concentration after rectal application seem to promote the development of a rectovaginal fistula.

OBJECTIVE Ergotamine tartrate suppositories are used for treatment of migraine headache attacks. Chronic abuse may lead to severe anorectal complications such as ulceration, stricture, and rectovaginal fistula. These complications are rare, and only sporadic reports may be found. Nevertheless,

OBJECTIVE To evaluate efficacy and safety of oral tacrolimus in cases of fistulizing Crohn's disease (FCD), which is refractory to conventional therapy including infliximab. METHODS Patients with fistulas, previously and unsuccessfully treated with all conventional therapy (i.e., antibiotics,