vinca difformis/悪性腫瘍

BACKGROUND ART Vinca alkaloids, originally isolated from the periwinkle plant [Vinca rosea Linn., now Cantharanthus roseus (L.) G. Don] are a family of indole-indoline dimeric compounds that contain a four-ring system containing an indole linked to a five-ring system containing an indoline. Two of

FIELD OF THE INVENTION This invention relates to the fields of biochemistry and medicine, and particularly to a pharmaceutical preparation which includes liposome-entrapped water soluble drug formulations, and methods of using such formulations to control the delivery of encapsulated agents to

FIELD OF THE INVENTION This invention relates to the fields of biochemistry and medicine, and particularly to a pharmaceutical preparation which includes liposome-entrapped water soluble drug formulations, and methods of using such formulations to control the delivery of encapsulated agents to

FIELD OF THE INVENTION This invention relates to the fields of biochemistry and medicine, and particularly to a pharmaceutical preparation which includes liposome-entrapped water soluble drug formulations, and methods of using such formulations to control the delivery of encapsulated agents to

The present invention is in the field of biochemistry and pharmacology. Specifically, the present invention relates to methods for treating cancers and malignancies by administering a pharmaceutically effective amount of a diiodo thyronine analogue having no significant hormonal activity and a vinca

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the use of vinca alkaloids in combatting tumors. 2. Discussion of the Background The dimeric alkaloids, vincristine and vinblastine, containing indol-indoline moieties from Catharanthus species are widely used as

BACKGROUND OF THE INVENTION Several naturally-occurring alkaloids obtainable from Vinca rosea have been found active in the treatment of experimental malignancies in animals. Among these are leurosine (U.S. Pat. No. 3,370,057), vincaleukoblastine (vinblastine) to be referred to hereinafter as VLB

BACKGROUND OF THE INVENTION Several naturally-occurring alkaloids obtainable from Vinca rosea have been found active in the treatment of experimental malignancies in animals. Among these are leurosine (U.S. Pat. No. 3,370,057), vincaleukoblastine (vinblastine) to be referred to hereinafter as VLB

BACKGROUND OF THE INVENTION Several naturally-occurring alkaloids obtainable from Vinca rosea have been found active in the treatment of experimental malignancies in animals. Among these are leurosine (U.S. Pat. No. 3,370,057), vincaleukoblastine (vinblastine) to be referred to hereinafter as VLB

TECHNICAL FIELD The present invention relates to the use of vinca alkaloids and their salts. More specifically, the present invention relates to agents that enhance insulin-producing and/or -secreting abilities of non-neoplastic cells derived from the pancreas, therapeutic agents for diabetes, blood