Use of PRP in Endometrial Reconstruction
키워드
요약
기술
The objective is to know the effect of these regenerative factors obtained from Platelet-Rich Plasma in an immunodeficient murine model with AS/EA Blood from patients with Asherman's Syndrome (AS) and Endometrial Atrophy (EA) will be collected, maintained under anticoagulant solution and after several centrifugations PRP will be obtained. Demonstration of a functional endometrium will be proved determining pregnancy and implantation rates as well as the number of live pups/pregnant female in our mice model. Also, the uterus histology will be analysed in treated and untreated mice
날짜
마지막 확인: | 04/30/2020 |
처음 제출: | 06/07/2017 |
제출 된 예상 등록: | 08/13/2017 |
처음 게시 됨: | 08/14/2017 |
제출 된 마지막 업데이트: | 05/13/2020 |
마지막 업데이트 게시: | 05/14/2020 |
실제 연구 시작 날짜: | 07/17/2017 |
예상 기본 완료 날짜: | 11/30/2020 |
예상 연구 완료 날짜: | 11/30/2020 |
상태 또는 질병
단계
자격 기준
공부할 수있는 연령 | 25 Years 에 25 Years |
공부할 수있는 성별 | Female |
샘플링 방법 | Probability Sample |
건강한 자원 봉사자를 받아들입니다 | 예 |
기준 | Inclusion Criteria: - Participants diagnosed with Asherman Syndrome and Endometrial Atrophy by Hysteroscopy. - No pregnancy after hormonal treatment. Exclusion Criteria: - Psychiatric diseases. |
결과
1 차 결과 측정
1. Endometrial thickness after reconstruction in murine model [through study completion, an average of 1 year]