Use of the Ozone in Periodontal Treatment
키워드
요약
기술
The study has been designed in a randomized parallelly-controlled and double-blinded design as a full-mouth clinical trial. The duration of the study was 1 month.
The study was performed with two groups; The Test Group, and the Control Group. SRP plus gaseous ozone [1 W (100 mJ, 10 Hz), (n=20)] was applied to the Test Group.
The Control Group, on the other hand, had SRP plus placebo (n=20). The patients were distributed in random order to the 2 groups (each group had 20 patients). One patient in the Ozone Group and 2 patients in the Control Group left the study.
The following clinical periodontal parameters were performed immediately before SRP (baseline), and 1 month after treatment for each test and control groups. Plaque index, GI, PD and CAL were recorded. All clinical parameter measurements were used a manual periodontal probe (PCP- 12, Hu-Friedy, Chicago, IL, USA).
The total antioxidant status, total oxidant status, nitric oxide, 8-hidroxi-deoksiguanosine, myeloperoxidase, glutathione, malondialdehyde and transforming growth factor-beta levels were determined in the saliva samples.
날짜
| 마지막 확인: | 01/31/2018 |
| 처음 제출: | 02/13/2018 |
| 제출 된 예상 등록: | 02/21/2018 |
| 처음 게시 됨: | 02/22/2018 |
| 제출 된 마지막 업데이트: | 02/21/2018 |
| 마지막 업데이트 게시: | 02/22/2018 |
| 실제 연구 시작 날짜: | 04/30/2012 |
| 예상 기본 완료 날짜: | 05/22/2015 |
| 예상 연구 완료 날짜: | 08/10/2016 |
상태 또는 질병
개입 / 치료
Device: Gaseous ozone group
Device: Control group
단계
팔 그룹
| 팔 | 개입 / 치료 |
|---|---|
| Active Comparator: Control group SRP plus placebo | Device: Control group only SRP |
| Experimental: Gaseous ozone group SRP plus gaseous ozone [1 W (100 mJ, 10 Hz)] | Device: Gaseous ozone group SRP plus gaseous ozone |
자격 기준
| 공부할 수있는 연령 | 30 Years 에 30 Years |
| 공부할 수있는 성별 | All |
| 건강한 자원 봉사자를 받아들입니다 | 예 |
| 기준 | Inclusion Criteria: 1. patients having had generalize CP which were agreed upon by consensus at the World Workshop in Periodontics in 1999 [24]; 2. three or more teeth having at least two quadrants with probing depth between 4 and 6 mm and radiographic signs of bone loss; 3. aged 30 years and above; 4. a minimum of 20 teeth. Exclusion Criteria: 1. received periodontal therapy within the last 12 months; 2. systemic diseases which could affect periodontal treatment outcomes; 3. having taken systemic antibiotics within the last 6 months; 4. pregnancy or breast-feeding for female patients. |
결과
1 차 결과 측정
1. Laboratory findings [One month]
2 차 결과 측정
1. Clinical findings [One month]
