Korean
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
ophiorrhiza pumila/neoplasms
링크가 클립 보드에 저장됩니다.
페이지 1 ...에서 20 결과
Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
Camptothecin (CPT) belongs to a group of monoterpenoidindole alkaloids (TIAs) and its derivatives such as irinothecan and topothecan have been widely used worldwide for the treatment of cancer, giving rise to rapidly increasing market demands. Genes from Catharanthus roseus encoding strictosidine
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
Background
Ophiorrhiza pumila, belonging to the genus Ophiorrhiza (Rubiaceae), is distributed throughout tropical and subtropical Asia. In this study, we evaluated for the first time the anti-proliferation and anti-migration effects of ethanol extract of O.Coupling deep transcriptome analysis with untargeted metabolic profiling in Ophiorrhiza pumila to further the understanding of the biosynthesis of the anti-cancer alkaloid camptothecin and anthraquinones.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
The Rubiaceae species, Ophiorrhiza pumila, accumulates camptothecin, an anti-cancer alkaloid with a potent DNA topoisomerase I inhibitory activity, as well as anthraquinones that are derived from the combination of the isochorismate and hemiterpenoid pathways. The biosynthesis of these secondary
Cancer chemopreventive potential of luteolin-7-O-glucoside isolated from Ophiorrhiza mungos Linn.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
The anticarcinogenic potential of the phytocompound Luteolin-7-O-Glucoside (LUT7G), isolated from the leaves of Ophiorrhiza mungos Linn, was studied against 4 different cancer cell lines (COLO 320 DM, AGS, MCF-7, and A549) and normal VERO cell line. The ability of LUT7G to induce apoptosis was
Transcription Factor OpWRKY3 Is Involved in the Development and Biosynthesis of Camptothecin and Its Precursors in Ophiorrhiza pumila Hairy Roots.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
The plant Ophiorrhiza pumila produces camptothecin (CPT), a kind of terpene indole alkaloid (TIAs) that has been widely used in treatment of cancer. Tryptophan-arginine-lysine-tyrosine (WRKY) transcription factors have been reported to play important roles in plant metabolism and development.
Asymmetric Total Synthesis and Evaluation of Antitumor Activity of Ophiorrhisine A and Its Derivatives.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
The first asymmetric total synthesis of ophiorrhisine A (1), a new cyclic tetrapeptide isolated from Ophiorrhiza nutans, was accomplished via an intramolecular aromatic nucleophilic substitution reaction (IMSNAr) of a linear tripeptide to construct a 14-membered paracyclophane ring, resulting in
Transcriptome-wide identification, characterization and phylogenomic analysis of cytochrome P450s from Nothapodytes nimmoniana reveal candidate genes involved in camptothecin biosynthetic pathway
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
The plant Nothapodytes nimmoniana is a source of important anticancer compound camptothecin (CPT) which is being used in the treatment of colorectal, lung and ovarian cancers. Camptothecin is biosynthesized by the combination of seco-iridoid and indole pathway in plants. Majority of the biosynthetic
Comparative studies on the camptothecin content from Nothapodytes foetida and Ophiorrhiza species.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
Camptothecin is an anticancer quinoline alkaloid effective against colon cancer. It acts by inhibition of the enzyme DNA topoisomerase I. A comparative study of camptothecin from the indigenous plants namely Nothapodytes foetida, Ophiorrhiza mungos and Ophiorrhiza rugosa indicated highest yields of
Antitumor activities of an anthraquinone fraction isolated from in vitro cultures of Ophiorrhiza rugosa var decumbens.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
The biological effects of the anthraquinone fraction (AQf) isolated from in vitro cultures of Ophiorrhiza rugosa Wall. var decumbens (Rubiaceae) were evaluated. AQf showed differential activity on reactive oxygen species; it mediated the generation of superoxide radical and inhibited hydroxyl
Cytotoxic and anti-inflammatory activities of secondary metabolites from Ophiorrhiza baviensis growing in Thua Thien Hue, Vietnam.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
A new ursane-type triterpene, 3β,23,24-trihydroxyurs-12-en-28-oic acid (1), together with eight known compounds (2-9) were isolated from the aerial parts of Ophiorrhiza baviensis. Among them, compounds 2-5 were found for the first time from the genus
Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
Camptothecin derivatives are clinically used anti-neoplastic alkaloids that biogenetically belong to monoterpenoid indole alkaloids. Camptothecin-related alkaloids from the methanol extracts of Ophiorrhiza pumila, Camptotheca acuminata and Nothapodytes foetida plants were profiled and identified
Camptothecin, over four decades of surprising findings.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
Camptothecin (CPT) is a modified monoterpene indole alkaloid produced by Camptotheca acuminata (Nyssaceae), Nothapodytes foetida, Pyrenacantha klaineana, Merrilliodendron megacarpum (Icacinaceae), Ophiorrhiza pumila (Rubiaceae), Ervatamia heyneana (Apocynaceae) and Mostuea brunonis (Gelsemiaceae),
Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
Plants produce a variety of toxic compounds, which are often used as anticancer drugs. The self-resistance mechanism to these toxic metabolites in the producing plants, however, remains unclear. The plant-derived anticancer alkaloid camptothecin (CPT) induces cell death by targeting DNA
Suppression of camptothecin biosynthetic genes results in metabolic modification of secondary products in hairy roots of Ophiorrhiza pumila.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
Camptothecin is a monoterpenoid indole alkaloid that exhibits anti-tumor activity. In Ophiorrhiza pumila, production of camptothecin and its related alkaloids was high in the hairy roots, but not in the cell suspension culture derived from hairy roots. To identify the intermediates in camptothecin
Production of camptothecin by hairy roots and regenerated transformed shoots of Ophiorrhiza rugosa var. decumbens.
등록 된 사용자 만 기사를 번역 할 수 있습니다.
로그인 / 가입
Camptothecin (CPT), the derivatives of which are used clinically for the treatment of metastatic colon cancer, is isolated from intact plants that can be subjected to environmental fluctuations. In vitro cultures may be an alternate and continuous source for year-round production of CPT. Since CPT
과학이 뒷받침하는 가장 완벽한 약초 데이터베이스
- 55 개 언어로 작동
- 과학이 뒷받침하는 약초 치료제
- 이미지로 허브 인식
- 인터랙티브 GPS지도-위치에 허브 태그 지정 (출시 예정)
- 검색과 관련된 과학 출판물 읽기
- 효과로 약초 검색
- 관심사를 정리하고 뉴스 연구, 임상 실험 및 특허를 통해 최신 정보를 확인하세요.
증상이나 질병을 입력하고 도움이 될 수있는 약초에 대해 읽고 약초를 입력하고 사용되는 질병과 증상을 확인합니다.
* 모든 정보는 발표 된 과학 연구를 기반으로합니다.
