Iron-deficiency

Anemia

Iron-biofortified beans

Control beans (Phaseolus vulgaris L Jamapa variety), identical in color and size

Control beans

Instituto Nacional de Salud Publica (INSP)

Iron-Biofortified Beans Intervention in Mexico

A Randomized Feeding Trial of Iron-Biofortified Beans in School Children in Mexico

Hb <115 g/L for <12 y; <120 g/L for >=12 y

Cornell University

Instituto Nacional de Salud Publica, Mexico

The study was a double-blind, cluster-randomized controlled trial (with randomization at the school level) of: (1) iron-biofortified black beans, compared to (2) a commercial variety of beans, with the intervention randomized at the school level. School administrators, children, research staff (i.e. managing the intervention, food weighing, assessment of outcomes), and laboratory staff were blinded to the intervention group.

The FeZnPM arm will consume iron- and zinc-biofortified pearl millet (ICTP8203-Fe).

The CtrlPM arm will consume conventional pearl millet three times per day, six days per week, for 9 months. Children are anticipated to consume 25-30 grams of the pearl millet at each feeding. The pearl millet will be prepared using a variety of recipes such as porridges, breads, and biscuits.

Iron Deficiency

Zinc Deficiency

Iron and zinc biofortified pearl millet will be consumed three times per day, six days per week, for 9 months. Children are anticipated to consume 25-30 grams of the pearl millet at each feeding. The pearl millet will be prepared using a variety of recipes such as porridges, breads, and biscuits.

FeZnPM

Conventional pearl millet will be consumed three times per day, six days per week, for 9 months. Children are anticipated to consume 25-30 grams of the pearl millet at each feeding. The pearl millet will be prepared using a variety of recipes such as porridges, breads, and biscuits.

CtrlPM

Centre for the Study of Social Change-Mumbai

St. John's Research Institute

S.N.D.T. Women's University

Effect of Iron/Zinc-Biofortified Pearl Millet on Growth and Immunity in Children Aged 12-18 Months in India

Effect of Iron- and Zinc-Biofortified Pearl Millet (ICTP8203-Fe) Consumption on Growth and Immunity in Children Aged 12-18 Months in India

Determined by serum ferritin, sTfR, and total body iron

As determined by length/height, weight, head circumference, and mid-upper arm circumference.

Measurement of T cell counts and vaccine response ELISA assays.

Higher-level, integrative cognitive abilities that require the coordination of multiple specific functions, such as problem-solving and exploratory behavior and global aspects of attention during free play with toys, will be assessed.

pennisetum centrasiaticum/inflammation

Iron-Biofortified Beans Intervention in Mexico

Effect of Iron/Zinc-Biofortified Pearl Millet on Growth and Immunity in Children Aged 12-18 Months in India

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