3 결과
The activity of three prenylhydroquinone glucosides (1-3) and four caffeoylquinic esters (4-7), obtained from Phagnalon rupestre, on elastase release, myeloperoxidase activity and superoxide and leukotriene B(4) production from polymorphonuclear leukocytes was determined. 4,5-Dicaffeoylquinic acid
The effect of Phagnalon rupestre MeOH extract on dinitrofluorobenzene- and sheep red blood cells-induced hypersensitivity was investigated. Eight compounds were identified: three dimethylallyl-hydroquinone glucosides (1 - 3), 3,5- and 4,5-di-O-caffeoylquinic acid methyl esters (4 and 5), their free
2-isoprenylhydroquinone-1-glucoside (1), 3,5-dicaffeoylquinic acid (2), and 3,5-dicaffeoylquinic acid methyl ester (3), isolated from Phagnalon rupestre, improved the contact hypersensitivity response to 2,4,6-trinitrochlorobenzene in mice. These phenolics reduced ear swelling and IL-1β content by